Orthobiologics treatment

Top Orthobiologics Treatment Hospital in Mumbai

Orthobiologics is a branch of medicine that uses natural substances from the body to promote healing and regeneration of musculoskeletal tissues. It is a promising and innovative approach to treat various orthopedic conditions, such as osteoarthritis, tendon injuries, ligament tears, bone fractures, and spinal disorders. Orthobiologics can help reduce pain, improve function, and enhance quality of life for patients who suffer from these conditions.

If you are looking for the best orthobiologics treatment hospital in Mumbai, you should consider Jaslok Hospital and Research Centre. Jaslok Hospital is one of the oldest and most reputed tertiary care, multi-specialty hospitals in the country. It has a dedicated team of experienced and internationally trained doctors who specialize in orthobiologics and regenerative medicine. The Department of RNR Medicine at Jaslok Hospital offers a comprehensive range of orthobiologics treatments, such as platelet-rich plasma (PRP), bone marrow concentrate (BMAC), adipose tissue-derived cells (ATC), and stem cell therapy. Jaslok Hospital also has state-of-the-art facilities and equipment to ensure the highest standards of safety and quality for its patients.

Discover the regenerative medicine for orthobiologics  in Mumbai, how it works, what are the types and benefits of orthobiologics treatments, and why you should choose Jaslok Hospital for your orthobiologics treatment in Mumbai.

 

 

What is Orthobiologics?

Orthobiologics is a term that combines two words: ortho and biologics. Ortho refers to the bones, joints, muscles, and tendons that make up the musculoskeletal system. Biologics refers to substances that are naturally derived from living organisms, such as cells, tissues, or proteins. Orthobiologics, therefore, are biological substances that are used to stimulate the body’s own healing and regenerative processes in the musculoskeletal system.

Orthobiologics can be obtained from the patient’s own body (autologous) or from a donor (allogeneic). The most common sources of orthobiologics are blood, bone marrow, and adipose tissue. These sources contain various types of cells and molecules that have the potential to repair and restore damaged or degenerated tissues. Some examples of these cells and molecules are platelets, growth factors, cytokines, stem cells, and extracellular matrix.

Orthobiologics can be administered in different ways, depending on the type and severity of the condition. Some of the common methods used at our hospital for orthobiologics  in Mumbai are :

Injection

Orthobiologics can be injected directly into the affected area, such as a joint, tendon, or ligament, using a syringe and a needle. This method is usually performed under local anesthesia and guided by ultrasound or X-ray imaging.

 

Implantation

It can be implanted into the injured site, such as a bone fracture or a spinal disc, using a surgical procedure. This method may require general anesthesia and hospitalization.

 

Infusion

Orthobiologics can be infused into the bloodstream, such as in the case of stem cell therapy, using an intravenous (IV) line. This method may require a blood test and a bone marrow aspiration before the infusion.

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How Does Orthobiologics Work

Orthobiologics operate by leveraging the body’s own capacity to heal and rejuvenate itself. When a musculoskeletal injury or ailment occurs, the body triggers an inflammatory reaction to eliminate damaged tissue and kickstart the repair process. However, there are instances where this response is inadequate or impaired, resulting in persistent pain, inflammation, and tissue breakdown.

Orthobiologics can enhance and augment the body’s healing and regenerative reaction. They provide the essential cells and molecules that can regulate inflammation, boost blood supply, attract stem cells, and facilitate tissue formation and restructuring. Moreover, Orthobiologics can potentially lessen the requirement for pain medication, steroid injections, or surgery—treatments that may carry side effects or entail complications.

 

Types of Orthobiologics

There are different types of orthobiologics that can be used for various orthopedic conditions. Some of the most common types are:

  • Extra-cellular matrices, like bone grafts, serve as scaffolds that fill voids in torn tissue. They provide the necessary support for bone growth and vasculature, essential for stimulating new bone formation.
  • Blood-derived substances, such as Autologous Conditioned Serum or Platelet-Rich Plasma (PRP), play a crucial role in the healing process. They deliver growth factors to the injured site, where they prompt cells to transform into “repair” cells, thereby accelerating the self-healing mechanism. This rejuvenates tissue injuries related to the musculoskeletal system, encompassing bones, muscles, ligaments, tendons, and joints. These substances are particularly effective for fractures, injured muscles, tendons, and ligaments.
  • Bone Marrow Aspirate Concentrate.

 

What is BMAC Therapy?

BMAC Therapy, or Bone Marrow Aspirate Concentrate Therapy, involves extracting bone marrow aspirate from the Iliac Crest, which serves as an excellent source of cells with the capability to differentiate into cartilage or bone.

Bone marrow contains various types of crucial cells:

  • Endothelial Progenitor Cells (EPC)
  • Mesenchymal Stem Cells (MSC)
  • Hematopoietic Stem Cells (HSC)

These cells play vital roles in the regenerative process. Specifically:

  • They promote cellular movement and aid in wound healing.
  • They help cells hold onto one another.
  • Endothelial Progenitor Cells (EPCs) assist in forming the structure of blood vessels and promote new blood vessel formation.
  • Hematopoietic stem cells play a role in regulating the regeneration process.
  • Increasing the concentration of cells speeds up the healing process.
  • They attract bone marrow progenitor cells to the site of injury.

 

 Applications of BMAC Therapy

Here are some potential applications of BMAC therapy:

Avascular Necrosis (AVN) of the Hip and Other Areas

In the early stages of Avascular Necrosis (AVN), alongside medication, Orthobiologic treatment using BMAC may be a viable option. This approach holds the potential to provide a concentrated dose of cells, which can play a supportive role in repairing the damaged bone. This, in turn, can contribute to pain relief and increase the likelihood of improvement, offering a ray of hope for hip preservation.

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Cartilage Defects and Tears

Any strain, stretch, or tear in the cartilage can result in cartilage defects. Typically, when referring to a cartilage tear, it usually pertains to an injury to the meniscus cartilage, which serves as a cushion between the shin bone and thighbone in the knee. Cartilage defects or meniscus tears often come with limited blood supply, making natural healing unlikely. This may eventually lead to the need for knee replacement in the future.

Risk Factors

Participation in sports like:

  • Football
  • Basketball
  • Soccer
  • Tennis

 

Conventional Treatments

  • Pain relievers such as ibuprofen or aspirin
  • Physical therapy
  • Use of braces or crutches
  • Arthroscopic surgery or meniscus repair (for severe cartilage defects)
  • Microfracture surgery
  • Autologous Cartilage Transfer

 

How do Orthobiologics Help Musculoskeletal Injuries?

Orthobiologics work by utilizing the body’s natural healing abilities. When a musculoskeletal injury occurs, the body initiates an inflammatory response to remove damaged tissue and start the repair process. However, in some cases, this response may be insufficient or impaired, leading to chronic pain, inflammation, and tissue degeneration.

Orthobiologics can enhance the body’s healing and regenerative response by providing the necessary cells and molecules. These components can modulate inflammation, stimulate blood supply, recruit stem cells, and facilitate tissue formation and remodeling. Additionally, orthobiologics can reduce the need for pain medication, steroid injections, or surgery, which may have side effects or complications.

 

Osteochondral Lesions

Osteochondral lesion occurs when there’s damage to both the cartilage and the underlying bone in a joint. This can happen due to various factors like injuries, tears, or wear and tear. It’s particularly common in joints like the knee, ankle, and elbow. This condition can lead to symptoms like pain, stiffness, instability, or a sensation of the joint getting stuck.

Risk Factors

  • Obesity
  • Trauma
  • Older Age
  • Sports Participation
  • Football
  • Soccer
  • Rugby
  • Golf

 

Conventional Treatments

  • Physical or Occupational Therapy
  • Braces or Assistive Devices
  • Surgery
  • Microfracture
  • Osteochondral Allograft Transplantation (OATS)

 

How do Orthobiologics Assist in Treatming Osteochondral Lesion?

Microfracture is a surgical technique aimed at healing damaged cartilage using the body’s own stem cells. Typically performed arthroscopically, it involves creating tiny holes in the damaged area, allowing new blood supply to reach the joint surface from the bone marrow. This supplies the damaged area with fresh stem cells, promoting the formation of new tissue. Additionally, surgeons fill these holes with a mixture of platelets and stem cells derived from bone marrow concentrate, further expediting the healing process.

Osteochondral Autograft Transplantation Surgery (OATS) is another procedure used to treat varying degrees of Osteochondral Lesions. It involves the transplantation of bone/cartilage to help regenerate damaged tissue, rather than replacing the joint with an implant. Doctors often incorporate stem cells or PRP into these grafts or scaffold materials to promote faster tissue reconstruction and improved mobility.

 

Traumatic Bone Loss

A fracture occurs when a bone is either partially or completely broken, and this can happen in various ways. Trauma can lead to significant damage to bone tissue, resulting in loss of function. It also triggers the immune system, influences the behavior of stem cells, and can impede the healing process, either partially or entirely.

Risk Factors

  • Trauma or Accidents
  • Osteoporosis
  • Stress or Overuse

 

Conventional Treatments

  • Plaster Cast Immobilization
  • Functional Braces
  • External and Internal Fixation
  • Traction

 

How Can Orthobiologics Help Traumatic Bone Loss?

In cases of non-unions or bone fractures, patients may have a reduced pool of Bone Marrow-Derived Stem Cells (BMSCs) and Growth Factors crucial for bone regeneration. Based on several clinical studies, our orthobiologics doctors in Mumbai advocate for the use of stem cells, either independently or in conjunction with other biological scaffold materials, to stimulate healing at the fracture site. Additionally, stem cells serve as a readily available source of osteoblast (bone) progenitors and secrete bioactive molecules that regulate cell differentiation and tissue regeneration. Bone Marrow Aspirate collected from the Iliac Crest, when processed, can yield an enriched concentration of platelets, stem, and progenitor cells, encouraging non-union healing with minimal complications.

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Benefits of Orthobiologics Treatment in Mumbai

Orthobiologics treatment in Mumbai at RNR Medicine can offer several benefits for patients who suffer from orthopedic conditions. Some of the orthobiologics treatment benefits are:

  • Natural and safe. Uses natural substances from the body or a donor, reducing infection, rejection, or allergic reactions. Avoids synthetic materials like metal implants.
  • Effective and long-lasting. Provides relief from pain, inflammation, and disability. Restores damaged tissues, improving quality of life and preventing further deterioration.
  • Minimally invasive and convenient. Orthobiologics is an outpatient procedure, no need for hospital stay. Uses minimally invasive techniques with minimal or no incision, reducing recovery time and need for rehabilitation.

 

Why Should You Choose Jaslok Hospital for Orthobiologics Treatment in Mumbai

Jaslok Hospital is the best orthobiologics treatment hospital in Mumbai for several reasons. Jaslok Hospital boasts state-of-the-art facilities and top-notch equipment, ensuring the highest standards of safety and quality for its patients. It houses a well-equipped laboratory and a meticulously controlled cell processing unit for the preparation of orthobiologics under sterile conditions. The hospital is also equipped with a modern operating theatre and an intensive care unit, where skilled and trained staff oversee orthobiologics treatments. Additionally, our hospital features a digital imaging and radiology department, utilizing high-resolution ultrasound or X-ray machines to guide and assess orthobiologics treatments.

Putting patient needs at the forefront, our team at Jaslok Hospital delivers patient-centered care and service. This approach prioritizes the patient’s preferences and requirements. The hospital offers tailored orthobiologics treatment in Mumbai, aligning with the patient’s condition, objectives, and expectations. Comprehensive and holistic care is a hallmark of Jaslok Hospital, encompassing pre-treatment consultation, assessment, and counseling, as well as post-treatment follow-up, feedback, and support. We maintain a commitment to transparent and affordable pricing, covering all costs and charges associated with orthobiologics treatment.

 

Best  Doctors for Orthobiologics Treatment  in Mumbai

Jaslok Hospital boasts a team of highly skilled and experienced doctors for orthobiologics treatment  in Mumbai, specializing in the field of regenerative medicine. These doctors have undergone extensive international training and hold certifications in the most advanced techniques of orthobiologics treatment. Their expertise is reflected in their substantial experience in successfully treating a range of orthopedic conditions using orthobiologics treatment in Mumbai, consistently delivering outstanding outcomes and high levels of patient satisfaction. With their unparalleled proficiency and dedication, patients at Jaslok Hospital receive care of the highest caliber in the realm of orthobiologics and regenerative medicine.

 

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